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after ThT-positive fibrils had formed, did not reduce fluorescence, indicating that preformed fibrils were not dissolved by the addition of the A-anticalin (Fig

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demonstrated in vitro the anti-leukemic activity of the novel CPT1A reversible inhibitor ST1326 on leukemia cell lines and primary cells obtained from patients with hematologic malignancies, which induces cell growth arrest, mitochondrial damage, and apoptosis 32